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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DCLRE1A All Species: 10
Human Site: S225 Identified Species: 20
UniProt: Q6PJP8 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6PJP8 NP_055696.3 1040 116422 S225 N Q T D N S V S N D P L L M T
Chimpanzee Pan troglodytes XP_508045 1040 116405 S225 N Q T D N S V S N D P L L M T
Rhesus Macaque Macaca mulatta XP_001090942 1039 116662 S225 S Q T D N S V S S D P L L M T
Dog Lupus familis XP_535018 1074 119811 V251 K Q S E D L N V S T H P S L V
Cat Felis silvestris
Mouse Mus musculus Q9JIC3 1026 113549 V224 K T E N L R K V S D H S L L M
Rat Rattus norvegicus NP_001099671 1026 112807 L216 L E E R R S V L L K T E D S R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513453 994 111830 E209 H L C N L E K E G S S R Q K Q
Chicken Gallus gallus Q5QJC4 972 108310 S187 V E R K M T C S T A A K S S C
Frog Xenopus laevis NP_001093331 932 103215 V148 A K E C P D G V M C S S A I P
Zebra Danio Brachydanio rerio XP_002664006 926 102909 H142 C M S T I P N H Y K R Y N H S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002321063 382 43088
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38961 484 55143
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 93.5 71.6 N.A. 62.8 61.8 N.A. 49.7 43.4 40.2 38.4 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.2 96 78.9 N.A. 72.5 72.5 N.A. 63.3 58.2 55.4 53.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 86.6 6.6 N.A. 13.3 13.3 N.A. 0 6.6 0 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 40 N.A. 33.3 20 N.A. 13.3 20 13.3 13.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: 20.6 N.A. N.A. 25.6 N.A. N.A.
Protein Similarity: 27.1 N.A. N.A. 34 N.A. N.A.
P-Site Identity: 0 N.A. N.A. 0 N.A. N.A.
P-Site Similarity: 0 N.A. N.A. 0 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 0 0 0 0 0 0 0 9 9 0 9 0 0 % A
% Cys: 9 0 9 9 0 0 9 0 0 9 0 0 0 0 9 % C
% Asp: 0 0 0 25 9 9 0 0 0 34 0 0 9 0 0 % D
% Glu: 0 17 25 9 0 9 0 9 0 0 0 9 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 9 0 9 0 0 0 0 0 0 % G
% His: 9 0 0 0 0 0 0 9 0 0 17 0 0 9 0 % H
% Ile: 0 0 0 0 9 0 0 0 0 0 0 0 0 9 0 % I
% Lys: 17 9 0 9 0 0 17 0 0 17 0 9 0 9 0 % K
% Leu: 9 9 0 0 17 9 0 9 9 0 0 25 34 17 0 % L
% Met: 0 9 0 0 9 0 0 0 9 0 0 0 0 25 9 % M
% Asn: 17 0 0 17 25 0 17 0 17 0 0 0 9 0 0 % N
% Pro: 0 0 0 0 9 9 0 0 0 0 25 9 0 0 9 % P
% Gln: 0 34 0 0 0 0 0 0 0 0 0 0 9 0 9 % Q
% Arg: 0 0 9 9 9 9 0 0 0 0 9 9 0 0 9 % R
% Ser: 9 0 17 0 0 34 0 34 25 9 17 17 17 17 9 % S
% Thr: 0 9 25 9 0 9 0 0 9 9 9 0 0 0 25 % T
% Val: 9 0 0 0 0 0 34 25 0 0 0 0 0 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 9 0 0 9 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _